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 Cognitive Neurology

Normal pressure hydrocephalus (NPH)

Normal pressure hydrocephalus (NPH)

Central nervous system
Central nervous system
Ventricles of the brain
Ventricles of the brain

Definition:

Normal pressure hydrocephalus (NPH) is a rise in cerebrospinal fluid (CSF) in the brain that affects brain function.

Alternative Names:
Hydrocephalus - idiopathic; Hydrocephalus - adult; Hydrocephalus - communicating; Extraventricular obstructive hydrocephalus
Causes, incidence, and risk factors:

Normal pressure hydrocephalus (NPH) is a form of hydrocephalus, also known as "water on the brain," which means there is too much fluid pressing on the brain.

NPH can occur without a known cause, or it may be caused by any condition that blocks the flow of cerebrospinal fluid (CSF). The fluid-filled chambers (ventricles) of the brain enlarge to fit the increased volume of CSF. They press down on and damage or destroy brain tissue.

Risk factors include:

The CSF is produced in normal amounts in these conditions, but it is prevented from being reabsorbed normally.

NPH is thought to account for about 5% of all dementias.

Symptoms:

The symptoms often begin slowly.

Early symptoms include:

  • Changes in gait, including inability to begin walking (gait apraxia)
  • Sudden fall without loss of consciousness or other symptoms (drop attacks)
  • Unsteady walking
  • Weakness of the legs

Symptoms as the disorder gets worse:

Signs and tests:

An examination shows walking (gait) changes related to the damage in the brain. Deep tendon reflexes may be increased in the lower legs.

Tests include:


Review Date: 2/13/2008
Reviewed By: Luc Jasmin, MD, PhD, Departments of Anatomy & Neurological Surgery, University of California, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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