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Alkalosis

Alkalosis

Kidneys
Kidneys

Definition:

Alkalosis is a condition in which the body fluids have excess base (alkali). This is the opposite of excess acid (acidosis).

Causes, incidence, and risk factors:

The lungs and kidneys regulate the acid/base status of the body. Decreased carbon dioxide (an acid) or increased bicarbonate (a base) levels make the body too alkaline, a condition called alkalosis.

Causes of alkalosis:

  • Respiratory alkalosis is caused by low carbon dioxide levels. Being at a high altitude or having a disease that reduces oxygen in the blood can cause you to breathe faster (hyperventilate), which lowers carbon dioxide levels.
  • Metabolic alkalosis is caused by too much bicarbonate in the blood.
  • Hypochloremic alkalosis is caused by an extreme lack or loss of chloride, which can occur with prolonged vomiting.
  • Hypokalemic alkalosis is caused by the kidneys' response to an extreme lack or loss of potassium, which can occur when people take certain diuretic medications.
  • Compensated alkalosis occurs when the body returns the acid/base balance to normal in cases of alkalosis, but bicarbonate and carbon dioxide levels remain abnormal.
Symptoms:
  • Confusion (can progress to stupor or coma)
  • Hand tremor
  • Light-headedness
  • Muscle twitching
  • Nausea, vomiting
  • Numbness or tingling in the face or extremities
  • Prolonged muscle spasms (tetany)
Signs and tests:

Tests of pH can show whether you have alkalosis or acidosis. Carbon dioxide and bicarbonate tests indicate whether the cause of alkalosis or acidosis is respiratory (breathing-related) or metabolic (kidney-related).

Tests for alkalosis include:

Review Date: 11/12/2007
Reviewed By: Charles Silberberg, D.O., Private Practice specializing in Nephrology, Affiliated with NY Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network.

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