Chronic urethritis is long-term inflammation of the urethra, the tube that carries urine from the body. Chronic urethritis continues for weeks to months.

Chronic urethritis is usually caused either by a bacterial infection or structural problem that results in narrowing of the urethra. The condition is associated with a variety of systemic diseases, emotional disorders, and sexually transmitted diseases such as chlamydia and gonorrhea.

E. coli, a common bacteria responsible for urinary tract infections, may also cause chronic urethritis. The use of personal hygiene products, especially feminine products, can cause chronic chemical urethritis.

Chronic urethritis occurs in both women and men. Painful urination and urinary frequency are the most common symptoms.

• Urinary frequency/urgency
• Urination discomfort, burning, or stinging of the urethra or lower abdomen during urination (see painful urination)
• Urethral discharge (bloody or pus-like, and often foul-smelling)

• Urinalysis may show infection or inflammation.
• Urine culture (clean catch) confirms infection and can show what bacteria is causing the infection.
• Urethral discharge culture or vaginal culture specimen(s) can rule out sexually transmitted diseases.
• Cystoscopy and urethroscopy are used to directly examine the urethra. These tests may reveal a urethral stricture (narrowing), a urethral diverticulum (out-pouching), or a mass (such as a urethral tumor).