Coccidiodin and spherulin are substances called antigens that are specifically associated with the fungus that causes coccidioidomycosis. One of these substances is injected just below the skin's surface, usually in the forearm. Your health care provider will look at your arm 24 hours and 48 hours after the test. If your body has antibodies to the coccidiomycosis fungus, your body will react to the antigen. The area of the shot will become red. |