Multiple Marker Screening Test (MMS)
The Multiple Marker Screening Test (MMS) is a
blood test performed between 15 and 19 weeks of
pregnancy to screen for Down syndrome and a birth
defect known as spina bifida. The MMS test is
commonly referred to as the quad screen test because
four substances are measured in the mother's blood.
One tube of blood is required for the quad screen
test and no special preparation is needed. For
example, you may eat prior to having your blood
sample drawn.
The four specific substances measured in the
mother’s blood originate from the fetus,
the placental tissue, or a combination of both.
These substances are called alpha feto-protein
(AFP), human chorionic gonadotropin (hCG), unconjugated
estriol (uE3), and inhibin A.
If you think that you may have a special risk
for having a child with birth defects, tell your
doctor or call one of our genetic counselors for
more information before you have the test.
Penn Ob/Gyn Care physicians and counselors provide
prenatal diagnosis, consultation and care at various
locations throughout the Philadelphia region.
Please call PennHealth at 1-800-789-PENN (7336)
for more information.
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