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Pregnancy Loss Evaluation

Pregnancy loss, particularly early miscarriage, is a common problem that affects many women and their partners. Losing a pregnancy is extremely difficult for the expectant parents, and even early losses cause frustration and grief. Many couples are anxious to understand why a miscarriage has occurred and may be hesitant to pursue another pregnancy until they know more about the cause of their loss.

What causes pregnancy loss?
While some miscarriages are caused by genetic or chromosomal abnormalities, other factors can contribute to repeated pregnancy loss. Testing can uncover problems within the uterus or cervix, as well as certain hormonal and immunological factors that could contribute to pregnancy loss.

Who can benefit from an evaluation?

  • Couples who have suffered three or more miscarriages.
  • Couples who have had two miscarriages and difficulty achieving pregnancy.
  • Couples with a family history of repeated pregnancy loss.
  • Couples with a maternal history of autoimmune disorders, thrombosis, lupus, or antiphospholipid antibodies.

Fortunately, careful evaluation often helps alleviate concerns about attempting future pregnancies. In many cases, following evaluation, the monitoring of future pregnancies can lead to the birth of a healthy baby.

Penn is a leading research center in the field of infertility and human reproduction. Based your clinical history and the stage of pregnancy at which you have experienced pregnancy losses, your ob/gyn may decide whether referral to our genetics program, infertility program, or a high-risk obstetrician would be helpful to determine the cause of your losses and treatment options.


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Need an appointment? Request one online 24 hours/day, 7 days/week or call 800-789-PENN (7366) to speak to a referral counselor.


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