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Monitoring for Rejection

Your body's response to any foreign object is to destroy it, so rejection is a normal reaction to the transplanted organ, which your body views as a foreign object. Immune cells immediately start fighting this foreign body. New organ rejection is normal and can occur at any time after a transplant. A few patients will experience one or more episodes of rejection during their recovery period. If left unchecked, the immune cells can damage or destroy a new organ, but most rejection cases are easily treated. Constant monitoring for rejection -- and prompt medical attention -- will keep your new organ functioning.

Rejection may be mild or severe. Take any symptoms of kidney rejection very seriously:

  • Fluid retention
  • Fatigue
  • Lethargy
  • Shortness of breath
  • Fever
  • Abdominal pain
  • Abnormal kidney function tests

In most cases, rejection can be controlled if treated promptly. That's why it's important to contact your transplant nurse or physician immediately if you experience any rejection symptoms.

However, rejection may occur without any symptoms and would only be found in blood tests. For this reason it is very important to keep your clinic appointments and obtain blood tests as prescribed by your physicians and coordinators. Your doctor may need to perform a biopsy to make a definitive diagnosis. If you are having a rejection episode, you may be admitted to the hospital for treatment.

If you received your kidney transplant at the Hospital of the University of Pennsylvania and are experiencing signs of organ rejection, call the transplant nurse at 215-662-6948 during office hours, 9:00 am to 5 pm. After business hours, call the main hospital number, 215-662-4000, and ask for the transplant coordinator on call.

Reviewed by Robert Grossman, MD
Last updated March 2004

 


Need an appointment? Request one online 24 hours/day, 7 days/week or call 800-789-PENN (7366) to speak to a referral counselor.

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